Summarising published results from spirometric surveys of COPD: the problem of inconsistent definitions.

ABSTRACT:

Setting

The use of different spirometric definitions for chronic obstructive pulmonary disease (COPD) has made an informative review of the available prevalence surveys impossible.

Objective

To derive adjustment factors that allow the comparison of studies using different spirometric criteria.

Methods

Pre- and post-bronchodilator one-second forced expiratory volume (FEV1) and forced vital capacity (FVC) values were taken from the Burden of Obstructive Lung Disease (BOLD) survey in 16 centres. Using a post-bronchodilator FEV1/FVC ratio less than the lower limit of normal (LLN) as our reference prevalence, we calculated simple multiplicative adjustments to transform other reported prevalence estimates to reference values. These adjustments were then tested on independen

SUBMITTER: Gupta RP 

PROVIDER: S-EPMC4531305 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature