The Effect of Adenotonsillectomy for Childhood Sleep Apnea on Cardiometabolic Measures.

ABSTRACT:

Study objectives

Obstructive sleep apnea syndrome (OSAS) has been associated with cardiometabolic disease in adults. In children, this association is unclear. We evaluated the effect of early adenotonsillectomy (eAT) for treatment of OSAS on blood pressure, heart rate, lipids, glucose, insulin, and C-reactive protein. We also analyzed whether these parameters at baseline and changes at follow-up correlated with polysomnographic indices.

Design

Data collected at baseline and 7-mo follow-up were analyzed from a randomized controlled trial, the Childhood Adenotonsillectomy Trial (CHAT).

Setting

Clinical referral setting from multiple centers.

Participants

There were 464 children, ages 5 to 9.9 y with OSAS without severe hypoxemia.

Interventions

Randomizatio

SUBMITTER: Quante M 

PROVIDER: S-EPMC4531407 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature