Well-Defined and Robust Rhodium Catalysts for the Hydroacylation of Terminal and Internal Alkenes.

ABSTRACT: A Rh-catalyst system based on the asymmetric ligand (t)Bu2PCH2P(o-C6H4OMe)2 is reported that allows for the hydroacylation of challenging internal alkenes with β-substituted aldehydes. Mechanistic studies point to the stabilizing role of both excess alkene and the OMe-group.

SUBMITTER: Prades A 

PROVIDER: S-EPMC4531818 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature