A critical appraisal of time-lapse imaging for embryo selection: where are we and where do we need to go?

ABSTRACT:

Purpose

The aim of this study was to undertake a critical appraisal of the available evidence for the use of time-lapse imaging for embryo selection in clinical IVF.

Methods

A literature search in PubMed, Scopus, Cochrane Central, ClinicalTrials.gov, Current Controlled Trials, and WHO International Clinical Trials Registry Platform was performed to identify randomized controlled trials that investigated the effect of time-lapse embryo selection and/or the time-lapse incubation system on ongoing pregnancy rate. We then performed a systematic review and assessed the relative risks (RRs) and 95 % confidence intervals (CIs) for ongoing pregnancy rates and the risk of bias of the eligible studies.

Results

We identified four eligible randomized studies, three of which inves

SUBMITTER: Racowsky C 

PROVIDER: S-EPMC4531870 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature