Unaltered timing of embryo development in women with polycystic ovarian syndrome (PCOS): a time-lapse study.

ABSTRACT:

Purpose

Polycystic ovarian syndrome (PCOS) is a common cause of female infertility. Factors other than anovulation, such as low embryo quality have been suggested to contribute to the infertility in these women. This 2-year retrospective study used timelapse technology to investigate the PCOS-influence on timing of development in the pre-implantation embryo (primary endpoint). The secondary outcome measure was live birth rates after elective single-embryo transfer.

Methods

In total, 313 embryos from 43 PCOS women, and 1075 embryos from 174 non-PCOS women undergoing assisted reproduction were included. All embryos were monitored until day 6. Differences in embryo kinetics were tested in a covariance regression model to account for potential confounding variables: female age,

SUBMITTER: Sundvall L 

PROVIDER: S-EPMC4531875 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature