Prenatal Docosahexaenoic Acid Supplementation and Offspring Development at 18 Months: Randomized Controlled Trial.

ABSTRACT:

Objective

We evaluated the effects of prenatal docosahexaenoic acid (DHA) supplementation on offspring development at 18 months of age.

Design

Randomized placebo double-blind controlled trial.

Settings

Cuernavaca, Mexico.

Participants and methods

We followed up offspring (n = 730; 75% of the birth cohort) of women in Mexico who participated in a trial of DHA supplementation during the latter half of pregnancy. We assessed the effect of the intervention on child development and the potential modifying effects of gravidity, gender, SES, and quality of the home environment.

Interventions or main exposures

400 mg/day of algal DHA.

Outcome measures

Child development at 18 months of age measured using the Spanish version of the Bayley Scales of Infant D

SUBMITTER: Ramakrishnan U 

PROVIDER: S-EPMC4532364 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature