The impact of vitamin D3 supplementation on muscle function among HIV-infected children and young adults: a randomized controlled trial.

ABSTRACT:

Objectives

We tested the hypothesis that daily vitD3 supplementation increases neuromuscular motor skills, jump power, jump energy, muscular force, and muscular strength.

Methods

This was a secondary analysis of a randomized controlled trial of 12-months of oral 7,000 IU/day vitD3 supplementation or placebo among 56 persons living with HIV aged 9-25 years. Neuromuscular motor skills were quantified using the Bruininks-Oseretsky Test of Motor Proficiency. Power was quantified using peak jump power, and energy was quantified using peak jump height. Muscular force was quantified using isometric ankle plantar- and dorsiflexion, isokinetic knee flexion and extension. Muscular strength was quantified using isometric handgrip strength.

Results

After 12-months, serum 25-hydro

SUBMITTER: Brown JC 

PROVIDER: S-EPMC4533987 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature