Allele, phenotype and disease data at Mouse Genome Informatics: improving access and analysis.

ABSTRACT: A core part of the Mouse Genome Informatics (MGI) resource is the collection of mouse mutations and the annotation phenotypes and diseases displayed by mice carrying these mutations. These data are integrated with the rest of data in MGI and exported to numerous other resources. The use of mouse phenotype data to drive translational research into human disease has expanded rapidly with the improvements in sequencing technology. MGI has implemented many improvements in allele and phenotype data annotation, search, and display to facilitate access to these data through multiple avenues. For example, the description of alleles has been modified to include more detailed categories of allele attributes. This allows improved discrimination between mutation types. Further, connections have been c

SUBMITTER: Bello SM 

PROVIDER: S-EPMC4534497 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature