Dataset of natural antisense transcripts in P. vivax clinical isolates derived using custom designed strand-specific microarray.

ABSTRACT: Natural antisense transcripts (NATs) have been detected in many organisms and shown to regulate gene expression. Similarly, NATs have also been observed in malaria parasites with most studies focused on Plasmodium falciparum. There were no reports on the presence of NATs in Plasmodium vivax, which has also been shown to cause severe malaria like P. falciparum, until a recent study published by us. To identify in vivo prevalence of antisense transcripts in P. vivax clinical isolates, we performed whole genome expression profiling using a custom designed strand-specific microarray that contains probes for both sense and antisense strands. Here we describe the experimental methods and analysis of the microarray data available in Gene Expression Omnibus (GEO) under GSE45165. Our data provides

SUBMITTER: Boopathi PA 

PROVIDER: S-EPMC4535868 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature