Clopidogrel and Aspirin versus Aspirin Alone for Stroke Prevention: A Meta-Analysis.

ABSTRACT:

Background and purpose

Antiplatelet therapy is widely used for the primary or secondary prevention of stroke. Drugs like clopidogrel have emerged as alternatives for traditional antiplatelet therapy, and dual therapy with clopidogrel and aspirin is of particular interest. We conducted this meta-analysis to systematically review studies about dual therapy comparing monotherapy with aspirin alone.

Methods

Randomized controlled trials were searched in PubMed (1966-May, 2015), EMBASE (1947-May, 2015), the Cochrane Central Register of Controlled Trials (CENTRAL) (1948-May, 2015), WHO International Clinical Trial (ICTRP) (2004-May, 2015), China Biology Medicine disc (CBM disc) (1978-May, 2015) and were included into the final analysis according to the definite inclusion criteria m

SUBMITTER: Tan S 

PROVIDER: S-EPMC4536208 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature