Design of the Bracing in Adolescent Idiopathic Scoliosis Trial (BrAIST).

ABSTRACT:

Study design

Descriptive.

Objective

To describe the design and development of Bracing in Adolescent Idiopathic Scoliosis Trial (BrAIST).

Summary of background data

Bracing has remained the standard of care for the nonoperative treatment of adolescent idiopathic scoliosis since the introduction of the Milwaukee brace in the late 1940s, but it has never been subjected to a rigorous evaluation of either its efficacy or its effectiveness. The BrAIST was designed to address the primary question: Do braces (specifically a thoracolumbosacral orthosis) lower the risk of curve progression to a surgical threshold (≥50°) in patients with adolescent idiopathic scoliosis relative to watchful waiting alone?

Methods

The authors describe the rationale for BrAIST, including the

SUBMITTER: Weinstein SL 

PROVIDER: S-EPMC4536980 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature