Development of Resistance to Pyrethroid in Culex pipiens pallens Population under Different Insecticide Selection Pressures.

ABSTRACT: Current vector control programs are largely dependent on pyrethroids, which are the most commonly used and only insecticides recommended by the World Health Organization for insecticide-treated nets (ITNs). However, the rapid spread of pyrethroid resistance worldwide compromises the effectiveness of control programs and threatens public health. Since few new insecticide classes for vector control are anticipated, limiting the development of resistance is crucial for prolonging efficacy of pyrethroids. In this study, we exposed a field-collected population of Culex pipiens pallens to different insecticide selection intensities to dynamically monitor the development of resistance. Moreover, we detected kdr mutations and three detoxification enzyme activities in order to explore the evolution

SUBMITTER: Shi L 

PROVIDER: S-EPMC4537097 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature