A Systematic Review of Mortality from Untreated Scrub Typhus (Orientia tsutsugamushi).

ABSTRACT:

Background

Scrub typhus, a bacterial infection caused by Orientia tsutsugamushi, is increasingly recognized as an important cause of fever in Asia, with an estimated one million infections occurring each year. Limited access to health care and the disease's non-specific symptoms mean that many patients are undiagnosed and untreated, but the mortality from untreated scrub typhus is unknown. This review systematically summarizes the literature on the untreated mortality from scrub typhus and disease outcomes.

Methodology/principal findings

A literature search was performed to identify patient series containing untreated patients. Patients were included if they were symptomatic and had a clinical or laboratory diagnosis of scrub typhus and excluded if they were treated with ant

SUBMITTER: Taylor AJ 

PROVIDER: S-EPMC4537241 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature