Desirability and feasibility of wireless electronic monitoring of medications in clinical trials.

ABSTRACT: Medication nonadherence is a vexing problem in health care necessitating patients and health professionals' efforts to prevent, minimize, or reverse it. Research participants' inconsistent medication taking obscures treatment efficacy and adds costs to biomedical research. Electronic monitoring devices (EMDs), like the Medication Event Monitoring System (MEMS), have grown in sophistication, providing precise, timely insights into individuals' medication-taking patterns across clinical populations. This article reports on the desirability and feasibility study of using a wireless EMD in clinical research to promote adherence to clinical regimens and research protocols. Nonadherence in transplant patients has been linked to late acute rejection and graft loss. High levels of adherence (97.7 

SUBMITTER: Robiner WN 

PROVIDER: S-EPMC4537458 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature