The effect of micro-ECoG substrate footprint on the meningeal tissue response.

ABSTRACT:

Objective

There is great interest in designing implantable neural electrode arrays that maximize function while minimizing tissue effects and damage. Although it has been shown that substrate geometry plays a key role in the tissue response to intracortically implanted, penetrating neural interfaces, there has been minimal investigation into the effect of substrate footprint on the tissue response to surface electrode arrays. This study investigates the effect of micro-electrocorticography (micro-ECoG) device geometry on the longitudinal tissue response.

Approach

The meningeal tissue response to two micro-ECoG devices with differing geometries was evaluated. The first device had each electrode site and trace individually insulated, with open regions in between, while the sec

SUBMITTER: Schendel AA 

PROVIDER: S-EPMC4539281 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature