Enteral glutamine supplementation in critically ill patients: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Glutamine (GLN) has been suggested to have a beneficial influence on outcomes of critically ill patients. However, recent large-scale trials have suggested harm associated with GLN supplementation. Recently, systematic reviews on the use of parenteral GLN have been published; however, less information is available on the role of enteral GLN. Therefore, the aim of this systematic review was to study the effects of enteral GLN supplementation in patients with critical illness.

Methods

We identified randomized controlled trials conducted from 1980 to 2014 with enterally administered GLN in adult critically ill patients. Studies of parenteral GLN only or combined enteral-parenteral GLN were excluded. The methodological quality of studies was scored, and trial data w

SUBMITTER: van Zanten AR 

PROVIDER: S-EPMC4539709 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature