Protective association of colonoscopy against proximal and distal colon cancer and patterns in interval cancer.

ABSTRACT:

Background

The protective effect of colonoscopy against proximal colorectal cancer is variable and depends on the detection and complete removal of precancerous polyps.

Objective

To estimate the efficacy of colonoscopy in a medical center with open-access screening colonoscopy since 1998.

Design

Nested case-control study with incidence density sampling.

Setting

University-affiliated Veterans Affairs Medical Center.

Patients

Colorectal cancer (CRC) cases and control subjects selected from screening age patients matched by age, gender, and date of first primary care visit.

Main outcome measurement

Colonoscopy preceding the CRC diagnosis date.

Results

A total of 20.2% of CRC cases had a colonoscopy in the preceding 10 years compared with 49.0%

SUBMITTER: Shergill AK 

PROVIDER: S-EPMC4540647 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature