Linc00675 is a novel marker of short survival and recurrence in patients with pancreatic ductal adenocarcinoma.

ABSTRACT:

Aim

To detect linc00675 expression in pancreatic ductal adenocarcinoma (PDAC), to analyze the relationship between the expression level of linc00675 and the clinical pathological characteristics, to explore the biological functions of linc00675, and to determine whether linc00675 has independent prognostic value in PDAC.

Methods

We studied linc00675 expression among eight histologically confirmed PDAC tissue samples and four chronic pancreatitis tissue samples through microarray screening. RT-qPCR was conducted to further investigate linc00675 expression in PDAC cell lines as well as archived tissues from a large cohort of PDAC patients. The correlations between the level of lnc00675 and clinicopathological characteristics and survival in patients with pancreatic cancer were

SUBMITTER: Li DD 

PROVIDER: S-EPMC4541386 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature