Salmon Gill Poxvirus, the Deepest Representative of the Chordopoxvirinae.

ABSTRACT:

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Poxviruses are large DNA viruses of vertebrates and insects causing disease in many animal species, including reptiles, birds, and mammals. Although poxvirus-like particles were detected in diseased farmed koi carp, ayu, and Atlantic salmon, their genetic relationships to poxviruses were not established. Here, we provide the first genome sequence of a fish poxvirus, which was isolated from farmed Atlantic salmon. In the present study, we used quantitative PCR and immunohistochemistry to determine aspects of salmon gill poxvirus disease, which are described here. The gill was the main target organ where immature and mature poxvirus particles were detected. The particles were detected in detaching, apoptotic respiratory epithelial cells preceding clinical disease in the fo

SUBMITTER: Gjessing MC 

PROVIDER: S-EPMC4542343 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature