Comparative Phylodynamics of Rabbit Hemorrhagic Disease Virus in Australia and New Zealand.

ABSTRACT:

Unlabelled

The introduction of rabbit hemorrhagic disease virus (RHDV) into Australia and New Zealand during the 1990s as a means of controlling feral rabbits is an important case study in viral emergence. Both epidemics are exceptional in that the founder viruses share an origin and the timing of their release is known, providing a unique opportunity to compare the evolution of a single virus in distinct naive populations. We examined the evolution and spread of RHDV in Australia and New Zealand through a genome-wide evolutionary analysis, including data from 28 newly sequenced RHDV field isolates. Following the release of the Australian inoculum strain into New Zealand, no subsequent mixing of the populations occurred, with viruses from both countries forming distinct groups. Str

SUBMITTER: Eden JS 

PROVIDER: S-EPMC4542356 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature