In-silico study of small cell lung cancer based on protein structure and function: A new approach to mimic biological system.

ABSTRACT: Lung cancer being the most common disease worldwide that leads to a number of deaths. A huge amount of effort has been done in screening trials for early diagnose treatment which increases the disease-free survival rate. Based on the expression of protein of mouse double minute 2 and tumor protein 53 complex, we have identified the antagonist for this complex that would facilitate the treatment for specific lung cancer. It is a complex disease that involves vast investigation for the characterization of a lung cancer and thus, computational study is being developed to mimic the in vivo system. In this work, a computational process was employed for the identification of these proteins, with a short and simple method to discover protein-protein interactions. Moreover, these proteins have mor

SUBMITTER: Sood N 

PROVIDER: S-EPMC4542399 | biostudies-literature | 2015 Jul-Sep

REPOSITORIES: biostudies-literature