How do base-pairing small RNAs evolve?

ABSTRACT: The increasing numbers of characterized base-pairing small RNAs (sRNAs) and the identification of these regulators in a broad range of bacteria are allowing comparisons between species and explorations of sRNA evolution. In this review, we describe some examples of trans-encoded base-pairing sRNAs that are species-specific and others that are more broadly distributed. We also describe examples of sRNA orthologs where different features are conserved. These examples provide the background for a discussion of mechanisms of sRNA evolution and selective pressures on the sRNAs and their mRNA target(s).

SUBMITTER: Updegrove TB 

PROVIDER: S-EPMC4542690 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature