Circulating immune/inflammation markers in Chinese workers occupationally exposed to formaldehyde.

ABSTRACT:

Background

Formaldehyde has been classified as a human myeloid leukemogen. However, the mechanistic basis for this association is still debated.

Objectives

We aimed to evaluate whether circulating immune/inflammation markers were altered in workers occupationally exposed to formaldehyde.

Methods

Using a multiplexed bead-based assay, we measured serum levels of 38 immune/inflammation markers in a cross-sectional study of 43 formaldehyde-exposed and 51 unexposed factory workers in Guangdong, China. Linear regression models adjusting for potential confounders were used to compare marker levels in exposed and unexposed workers.

Results

We found significantly lower circulating levels of two markers among exposed factory workers compared with unexposed controls that

SUBMITTER: Seow WJ 

PROVIDER: S-EPMC4542853 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature