Bispectral Index in Evaluating Effects of Sedation Depth on Drug-Induced Sleep Endoscopy.

ABSTRACT:

Objective

To evaluate the effect of sedation depth on drug-induced sleep endoscopy (DISE).

Methods

Ninety patients with obstructive sleep apnea (OSA) and 18 snorers underwent polysomnography and DISE under bispectral index (BIS)-guided propofol infusion at two different sedation levels: BIS 65-75 (light sedation) and 50-60 (deep sedation).

Results

For the patients with OSA, the percentages of velopharynx, oropharynx, hypopharynx, and larynx obstructions under light sedation were 77.8%, 63.3%, 30%, and 33.3%, respectively. Sedation depth was associated with the severity of velopharynx and oropharynx obstruction, oropharynx obstruction pattern, tongue base obstruction, epiglottis anteroposterior prolapse and folding, and arytenoid prolapse. In comparison, OSA severity w

SUBMITTER: Lo YL 

PROVIDER: S-EPMC4543245 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature