Genetic factors associated with exercise performance in atmospheric hypoxia.

ABSTRACT:

Background and objective

'Natural selection' has been shown to have enriched the genomes of high-altitude native populations with genetic variants of advantage in this hostile hypoxic environment. In lowlanders who ascend to altitude, genetic factors may also contribute to the substantial interindividual variation in exercise performance noted at altitude. We performed a systematic literature review to identify genetic variants of possible influence on human hypoxic exercise performance, commenting on the strength of any identified associations.

Criteria for considering studies for this review

All studies of the association of genetic factors with human hypoxic exercise performance, whether at sea level using 'nitrogen dilution of oxygen' (normobaric hypoxia), or at altitude

SUBMITTER: Hennis PJ 

PROVIDER: S-EPMC4544548 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature