Proportion of colon cancer attributable to lifestyle in a cohort of US women.

ABSTRACT:

Background

Many modifiable lifestyle factors have been associated with colon cancer risk, but less is known about their effect on disease when considered together. Estimating the proportion of colon cancer cases that could be prevented by the adoption of combined modifiable lifestyle behaviors will provide important insights into disease prevention.

Methods

In the Nurses' Health Study, we defined a low-risk group according to a combination of six factors: body mass index < 25 kg/m(2), physical activity of ≥ 21 metabolic equivalent of task per week, alcohol consumption ≤ 30 g/day, cigarette smoking <10 pack-years before the age of 30, current use of multivitamins for ≥ 15 years, and total calcium intake ≥ 700 mg/day. A composite risk score index was created and the population

SUBMITTER: Erdrich J 

PROVIDER: S-EPMC4545459 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature