Parietal and Frontal Cortex Encode Stimulus-Specific Mnemonic Representations during Visual Working Memory.

ABSTRACT: Working memory (WM) enables the storage and manipulation of information in an active state. WM storage has long been associated with sustained increases in activation across a network of frontal and parietal cortical regions. However, recent evidence suggests that these regions primarily encode information related to general task goals rather than feature-selective representations of specific memoranda. These goal-related representations are thought to provide top-down feedback that coordinates the representation of fine-grained details in early sensory areas. Here, we test this model using fMRI-based reconstructions of remembered visual details from region-level activation patterns. We could reconstruct high-fidelity representations of a remembered orientation based on activation patterns

SUBMITTER: Ester EF 

PROVIDER: S-EPMC4545683 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature