A randomized controlled trial of green tea catechins in protection against ultraviolet radiation-induced cutaneous inflammation.

ABSTRACT:

Background

Safe systemic protection from the health hazards of ultraviolet radiation (UVR) in sunlight is desirable. Green tea is consumed globally and is reported to have anti-inflammatory properties, which may be mediated through the impact on cyclooxygenase and lipoxygenase pathways. Recent data suggest that green tea catechins (GTCs) reduce acute UVR effects, but human trials examining their photoprotective potential are scarce.

Objective

We performed a double-blind, randomized, placebo-controlled trial to examine whether GTCs protect against clinical, histologic, and biochemical indicators of UVR-induced inflammation.

Design

Healthy adults (aged 18-65 y, phototypes I-II) were randomly allocated to 1350 mg encapsulated green tea extract (540 mg GTC) with 50 mg vit

SUBMITTER: Farrar MD 

PROVIDER: S-EPMC4548173 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature