Genomic Variants Revealed by Invariably Missing Genotypes in Nelore Cattle.

ABSTRACT: High density genotyping panels have been used in a wide range of applications. From population genetics to genome-wide association studies, this technology still offers the lowest cost and the most consistent solution for generating SNP data. However, in spite of the application, part of the generated data is always discarded from final datasets based on quality control criteria used to remove unreliable markers. Some discarded data consists of markers that failed to generate genotypes, labeled as missing genotypes. A subset of missing genotypes that occur in the whole population under study may be caused by technical issues but can also be explained by the presence of genomic variations that are in the vicinity of the assayed SNP and that prevent genotyping probes from annealing. The latt

SUBMITTER: da Silva JM 

PROVIDER: S-EPMC4549312 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature