The association between miR-499 polymorphism and cancer susceptibility: a meta-analysis.

ABSTRACT:

Background

MicroRNAs are a class of new noncoding RNA that play important roles in the pathogenesis of tumor. Rs3746444 in miR-499 is suggested to be associated with cancer susceptibility. In the present study, we assess the association between miR-499 rs3746444 polymorphism and cancer susceptibility through a meta-analysis.

Methods

We searched relevant articles from the PubMed and Embase databases. We screened all the resulting articles for adherence to the inclusion and exclusion criteria. The associations between miR-499 polymorphism and cancer susceptibility were estimated by computing the odds ratios (ORs) and 95% confidence intervals (CIs). All analyses were performed using Stata software.

Results

There are 18 datasets included in the analysis. Statistically sig

SUBMITTER: Xu Z 

PROVIDER: S-EPMC4550183 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature