Macronutrient intake and body composition changes during anti-tuberculosis therapy in adults.

ABSTRACT:

Background

Malnutrition is common in patients with active tuberculosis (TB), yet little information is available on serial dietary intake or body composition in TB disease.

Objective

To evaluate macronutrient intake and body composition in individuals with newly diagnosed TB over time.

Design

Adults with active pulmonary TB (n = 191; 23 with multidrug resistant TB (MDR-TB) and 36 culture-negative household contacts (controls) enrolled in a clinical trial of high-dose cholecalciferol (vitamin D3) were studied. Macronutrient intake was determined at baseline, 8 and 16 weeks. Serial body composition was assessed by body mass index (BMI; kg/m(2)) and bioelectrical impedance analysis (BIA) to estimate fat mass and fat-free mass. Descriptive statistics, repeated measures AN

SUBMITTER: Frediani JK 

PROVIDER: S-EPMC4550569 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature