Comprehensive Cardiovascular Risk Factor Control Improves Survival: The BARI 2D Trial.

ABSTRACT:

Background

It is unclear whether achieving multiple risk factor (RF) goals through protocol-guided intensive medical therapy is feasible or improves outcomes in type 2 diabetes mellitus.

Objectives

This study sought to quantify the relationship between achieved RF goals in the BARI 2D (Bypass Angioplasty Investigation Revascularization 2 Diabetes) trial and cardiovascular events/survival.

Methods

We performed a nonrandomized analysis of survival/cardiovascular events and control of 6 RFs (no smoking, non-high-density lipoprotein cholesterol <130 mg/dl, triglycerides <150 mg/dl, blood pressure [systolic <130 mm Hg; diastolic <80 mm Hg], glycosylated hemoglobin <7%) in BARI 2D. Cox models with time-varying number of RFs in control were adjusted for baseline number of RF

SUBMITTER: Bittner V 

PROVIDER: S-EPMC4550809 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature