Intermingled Klebsiella pneumoniae Populations Between Retail Meats and Human Urinary Tract Infections.

ABSTRACT:

Background

Klebsiella pneumoniae is a common colonizer of the gastrointestinal tract of humans, companion animals, and livestock. To better understand potential contributions of foodborne K. pneumoniae to human clinical infections, we compared K. pneumoniae isolates from retail meat products and human clinical specimens to assess their similarity based on antibiotic resistance, genetic relatedness, and virulence.

Methods

Klebsiella pneumoniae was isolated from retail meats from Flagstaff grocery stores in 2012 and from urine and blood specimens from Flagstaff Medical Center in 2011-2012. Isolates underwent antibiotic susceptibility testing and whole-genome sequencing. Genetic relatedness of the isolates was assessed using multilocus sequence typing and phylogenetic analyses.

SUBMITTER: Davis GS 

PROVIDER: S-EPMC4551003 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature