Incidence of and risk factors for type-specific anal human papillomavirus infection among HIV-positive MSM.

ABSTRACT:

Objective

HIV-positive MSM are at increased risk of anal human papillomavirus (HPV) infection compared with men in the general population, and little is known about the natural history of anal HPV infection in this population. The objective of this study was to determine the incidence of and risk factors for anal type-specific HPV infection.

Design

Prospective cohort study.

Methods

HIV-positive MSM were evaluated for anal HPV DNA, lifestyle factors, and sexual risk behaviors every 6 months for at least 2 years.

Results

The overall incidence rate of detectable type-specific anal HPV infection was 21.3 per 100 person-years [95% confidence interval (CI) 17.7-25.4] and was 13.3/100 person-years (10.5-16.6) for oncogenic HPV types. The most common incident infection

SUBMITTER: Hernandez AL 

PROVIDER: S-EPMC4551512 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature