Escher: A Web Application for Building, Sharing, and Embedding Data-Rich Visualizations of Biological Pathways.

ABSTRACT: Escher is a web application for visualizing data on biological pathways. Three key features make Escher a uniquely effective tool for pathway visualization. First, users can rapidly design new pathway maps. Escher provides pathway suggestions based on user data and genome-scale models, so users can draw pathways in a semi-automated way. Second, users can visualize data related to genes or proteins on the associated reactions and pathways, using rules that define which enzymes catalyze each reaction. Thus, users can identify trends in common genomic data types (e.g. RNA-Seq, proteomics, ChIP)--in conjunction with metabolite- and reaction-oriented data types (e.g. metabolomics, fluxomics). Third, Escher harnesses the strengths of web technologies (SVG, D3, developer tools) so that visualizat

SUBMITTER: King ZA 

PROVIDER: S-EPMC4552468 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature