Risk factors for poor visual outcome in patients with idiopathic intracranial hypertension.

ABSTRACT:

Objectives

Determine potential risk factors for progressive visual field loss in the Idiopathic Intracranial Hypertension Treatment Trial, a randomized placebo-controlled trial of acetazolamide in patients with idiopathic intracranial hypertension and mild visual loss concurrently receiving a low sodium, weight reduction diet.

Methods

Logistic regression and classification tree analyses were used to evaluate potential risk factors for protocol-defined treatment failure (>2 dB perimetric mean deviation [PMD] change in patients with baseline PMD -2 to -3.5 dB or >3 dB PMD change with baseline PMD -3.5 to -7 dB).

Results

Seven participants (6 on diet plus placebo) met criteria for treatment failure. The odds ratio for patients with grades III to V papilledema vs those wi

SUBMITTER: Wall M 

PROVIDER: S-EPMC4553022 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature