Poor early relapse recovery affects onset of progressive disease course in multiple sclerosis.

ABSTRACT:

Objective

To evaluate the relationship between early relapse recovery and onset of progressive multiple sclerosis (MS).

Methods

We studied a population-based cohort (105 patients with relapsing-remitting MS, 86 with bout-onset progressive MS) and a clinic-based cohort (415 patients with bout-onset progressive MS), excluding patients with primary progressive MS. Bout-onset progressive MS includes patients with single-attack progressive and secondary progressive MS. "Good recovery" (as opposed to "poor recovery") was assigned if the peak deficit of the relapse improved completely or almost completely (patient-reported and examination-confirmed outcome measured ≥6 months post relapse). Impact of initial relapse recovery and first 5-year average relapse recovery on cumulative in

SUBMITTER: Novotna M 

PROVIDER: S-EPMC4553030 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature