Protein-Protein Interaction Network could reveal the relationship between the breast and colon cancer.

ABSTRACT:

Aim

This study is aimed to elicit the possible correlation between breast and colon cancer from molecular prospective by analyzing and comparing pathway-based biomarkers.

Background

Breast and colon cancer are known to be frequent causes of morbidity and mortality in men and women around the world. There is some evidence that while the incident of breast cancer in young women is high, it is reported lower in the aged women. In fact, aged women are more prone to colorectal cancer than older men. . In addition, many studies showed that several biomarkers are common among these malignancies.

Patients and methods

The genes were retrieved and compared from KEGG database and WikiPathway, and subsequently, protein-protein interaction (PPI) network was constructed and analyze

SUBMITTER: Zamanian-Azodi M 

PROVIDER: S-EPMC4553162 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature