Hearing Assessment after Treatment of Nasopharyngeal Carcinoma with CRT and IMRT Techniques.

ABSTRACT:

Objectives

This study analyzed the long-term hearing loss after treatment of primary nasopharyngeal carcinoma to elucidate its causal factors.

Methods

Ninety-two nasopharyngeal carcinoma patients were treated with radiotherapy or chemoradiotherapy. Pure tone audiometry was performed before the therapy and annually up to 9 years after completing treatment. The hearing thresholds were corrected for age-related deterioration and compared to the results without adjusting for age.

Results

The mean air and bone conduction threshold with and without correction for age-related deterioration differed significantly 2-9 years after completing radiotherapy (p < 0.05). The audiometry results with age correction showed a flattened configuration compared to the results without age c

SUBMITTER: Hwang CF 

PROVIDER: S-EPMC4553178 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature