Tissue-Specific Immune Gene Expression in the Migratory Locust, Locusta Migratoria.

ABSTRACT: The ability of hosts to respond to infection involves several complex immune recognition pathways. Broadly conserved pathogen-associated molecular patterns (PAMPs) allow individuals to target a range of invading microbes. Recently, studies on insect innate immunity have found evidence that a single pathogen can activate different immune pathways across species. In this study, expression changes in immune genes encoding peptidoglycan-recognition protein SA (PGRP-SA), gram-negative binding protein 1 (GNBP1) and prophenoloxidase (ProPO) were investigated in Locusta migratoria, following an immune challenge using injected lipopolysaccharide (LPS) solution from Escherichia coli. Since immune activation might also be tissue-specific, gene expression levels were followed across a range of tissue

SUBMITTER: Pulpitel T 

PROVIDER: S-EPMC4553485 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature