Association of comorbidities with postoperative in-hospital mortality: a retrospective cohort study.

ABSTRACT: The purpose of this article is to evaluate the American Society of Anesthesiologists Physical Status (ASA PS) and the Charlson comorbidity index (CCI) for the prediction of postoperative mortality. The ASA PS has been suggested to be equally good as the CCI in predicting postoperative outcome. However, these scores have never been compared in a broad surgical population. We conducted a retrospective cohort study in a German tertiary care university hospital. Predictive accuracy was compared using the area under the receiver-operating characteristic curves (AUROC). In a post hoc approach, a regression model was fitted and cross-validated to estimate the association of comorbidities and intraoperative factors with mortality. This model was used to improve prediction by recalibrating the CCI

SUBMITTER: Kork F 

PROVIDER: S-EPMC4554144 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature