Enhancing the protein resistance of silicone via surface-restructuring PEO-silane amphiphiles with variable PEO length.

ABSTRACT: Silicones with superior protein resistance were produced by bulk-modification with poly(ethylene oxide) (PEO)-silane amphiphiles that demonstrated a higher capacity to restructure to the surface-water interface versus conventional non-amphiphilic PEO-silanes. The PEO-silane amphiphiles were prepared with a single siloxane tether length but variable PEO segment lengths: α-(EtO)₃Si(CH₂)₂-oligodimethylsiloxane₁₃-block-poly(ethylene oxide) _n -OCH₃ (n = 3, 8, and 16). Conventional PEO-silane analogues (n = 3, 8 and 16) as well as a siloxane tether-silane (i.e. no PEO segment) were prepared as controls. When surface-grafted onto silicon wafer, PEO-silane amphiphiles produced surfaces that were more hydr

SUBMITTER: Rufin MA 

PROVIDER: S-EPMC4554761 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature