Structure of RizA, an L-amino-acid ligase from Bacillus subtilis.

ABSTRACT: RizA is an L-amino-acid ligase from Bacillus subtilis that participates in the biosynthesis of rhizocticin, an oligopeptide antibiotic. The substrate-free form of RizA has been crystallized and the structure was solved at 2.8 Å resolution. The amino-acid-binding site appears to be capable of accommodating multiple amino acids, consistent with previous biochemical studies.

SUBMITTER: Kagawa W 

PROVIDER: S-EPMC4555917 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature