Selective Vaporization of Superheated Nanodroplets for Rapid, Sensitive, Acoustic Biosensing.

ABSTRACT: Superheated perfluorocarbon nano-droplets exhibit promise as sensitive acoustic biosensors. Aggregation of biotin-decorated lipid-shelled droplets by streptavidin greatly increases the yield of bubbles formed by ultrasound-induced vaporization. Streptavidin is sensed down to 1 × 10(-13) m, with differentiable signal appearing in as little as two minutes, using a scalable assay without washing, processing, or development steps.

SUBMITTER: Chattaraj R 

PROVIDER: S-EPMC4556242 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature