The female urinary microbiome in urgency urinary incontinence.

ABSTRACT:

Objective

The purpose of this study was to characterize the urinary microbiota in women who are planning treatment for urgency urinary incontinence and to describe clinical associations with urinary symptoms, urinary tract infection, and treatment outcomes.

Study design

Catheterized urine samples were collected from multisite randomized trial participants who had no clinical evidence of urinary tract infection; 16S ribosomal RNA gene sequencing was used to dichotomize participants as either DNA sequence-positive or sequence-negative. Associations with demographics, urinary symptoms, urinary tract infection risk, and treatment outcomes were determined. In sequence-positive samples, microbiotas were characterized on the basis of their dominant microorganisms.

Results

Mo

SUBMITTER: Pearce MM 

PROVIDER: S-EPMC4556587 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature