Validation of a photographic vitreous haze grading technique for clinical trials in uveitis.

ABSTRACT:

Purpose

To validate a photographic vitreous haze grading technique using a 9-step logarithmic scale in patients enrolled in a randomized, controlled clinical trial in uveitis.

Design

Retrospective study of clinical trials methodology.

Methods

Setting

University-based department of ophthalmology.

Study population

Baseline fundus photographs of patients with intermediate uveitis, posterior uveitis, or panuveitis enrolled in the Multicenter Uveitis Steroid Treatment (MUST) trial.

Observational procedure

Grading of vitreous haze using a previously described photographic scale. Regrading of a subset of photographs to assess intraobserver agreement.

Main outcome measures

Interobserver and intraobserver intraclass correlation for photographic haz

SUBMITTER: Madow B 

PROVIDER: S-EPMC4556733 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature