Evolutionary history inferred from the de novo assembly of a nonmodel organism, the blue-eyed black lemur.

ABSTRACT: Lemurs, the living primates most distantly related to humans, demonstrate incredible diversity in behaviour, life history patterns and adaptive traits. Although many lemur species are endangered within their native Madagascar, there is no high-quality genome assembly from this taxon, limiting population and conservation genetic studies. One critically endangered lemur is the blue-eyed black lemur Eulemur flavifrons. This species is fixed for blue irises, a convergent trait that evolved at least four times in primates and was subject to positive selection in humans, where 5' regulatory variation of OCA2 explains most of the brown/blue eye colour differences. We built a de novo genome assembly for E. flavifrons, providing the most complete lemur genome to date, and a high confidence consensu

SUBMITTER: Meyer WK 

PROVIDER: S-EPMC4557055 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature