Complete genome sequence of two genotype III Japanese encephalitis virus isolates from West Bengal, India.

ABSTRACT:

Background & objectives

Japanese encephalitis (JE), caused by a mosquito-borne virus JE virus (JEV), is a serious health problem in West Bengal, India. In this study, we report the complete genome sequence of two JEV isolates from West Bengal. The amino acid and nucleotide sequence homology was compared with other Indian strains.

Methods

Two JEV isolates (IND-WB-JE1 and IND-WB-JE2) obtained in 2008 and 2010, respectively, from two districts of the State of West Bengal, respectively were analyzed for genetic variations by sequencing the 10934 bp whole genome of the virus. Of these two districts, one was covered under JE vaccination programme in 2007.

Results

Phylogenetic analysis showed that both the isolates belonged to the genotype III. A total of 16 mutations were i

SUBMITTER: Taraphdar D 

PROVIDER: S-EPMC4557254 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature