Reproducibility of the Structural Brain Connectome Derived from Diffusion Tensor Imaging.

ABSTRACT:

Rationale

Disruptions of brain anatomical connectivity are believed to play a central role in several neurological and psychiatric illnesses. The structural brain connectome is typically derived from diffusion tensor imaging (DTI), which may be influenced by methodological factors related to signal processing, MRI scanners and biophysical properties of neuroanatomical regions. In this study, we evaluated how these variables affect the reproducibility of the structural connectome.

Methods

Twenty healthy adults underwent 3 MRI scanning sessions (twice in the same MRI scanner and a third time in a different scanner unit) within a short period of time. The scanning sessions included similar T1 weighted and DTI sequences. Deterministic or probabilistic tractography was performed

SUBMITTER: Bonilha L 

PROVIDER: S-EPMC4557836 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature