Influence of leptin, adiponectin, and resistin on the association between abdominal adiposity and arterial stiffness.

ABSTRACT:

Background

Adiposity is associated with arterial stiffness, and both adiposity and arterial stiffness independently predict morbidity and mortality. Because adipocytes account for most adipokine production, the objectives of this study were to examine the influence of adipokines such as leptin, adiponectin, and resistin on the relationship between abdominal adiposity and arterial stiffness.

Methods

This is a cross-sectional analysis of data from the Baltimore Longitudinal Study of Aging (BLSA). Adiposity was measured as kilograms of abdominal adipose tissue using dual-energy X-ray absorptiometry (DXA). Arterial stiffness was assessed as carotid-femoral pulse wave velocity (PWV). Leptin, adiponectin, and resistin were assayed in fasting serum samples. The influence of adipoki

SUBMITTER: Windham BG 

PROVIDER: S-EPMC4557869 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature